amaurosis

American  

[am-aw-roh-sis] / ˌæm ɔˈroʊ sɪs /

noun

1. partial or total loss of sight, especially in the absence of a gross lesion or injury.

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amaurosis British  

/ ˌæmɔːˈrəʊsɪs, ˌæmɔːˈrɒtɪk /

noun

1. pathol blindness, esp when occurring without observable damage to the eye

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Other Word Forms

• amaurotic
  adjective

Etymology

Origin of amaurosis

1650–60; < Greek: darkening, hindrance to sight, equivalent to amaur ( ós ) dim, dark + -ōsis -osis

Example Sentences

The findings deepen understanding of how mutations in the RPE65 enzyme cause retinal diseases, especially Leber congenital amaurosis, a devastating childhood blinding disease.

From Science Daily • Feb. 22, 2024

Toben has a rare genetic condition called Leber's congenital amaurosis.

From BBC • May 27, 2022

Trial participants have Leber congenital amaurosis type 10, caused by a mutated gene that the trial aimed to fix.

From Science Magazine • Oct. 6, 2021

Last July, the pharmaceutical companies Editas Medicine in Cambridge, Massachusetts, and Allergan in Dublin launched a trial to treat the genetic disorder Leber congenital amaurosis 10, which can cause blindness, by editing eye cells.

From Nature • Jan. 5, 2020

In this case there was partial amaurosis in both sides, although nothing of disease could be discovered in the left eye.

From The Dog by Youatt, William