amitriptyline
Americannoun
noun
Etymology
Origin of amitriptyline
Perhaps ami(no)- + trypt(ophan) + (meth)yl + -ine 2
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Sanchez examined four psychoactive pharmaceuticals frequently detected in treated wastewater: carbamazepine, lamotrigine, amitriptyline, and fluoxetine.
From Science Daily ● Mar. 15, 2026
Dr Toby Pillinger says: Sarah should have an antidepressant that avoids weight gain, such as agomelatine, sertraline or venlafaxine rather than amitriptyline or mirtazapine which are more likely to increase weight.
From BBC ● Oct. 21, 2025
The first three “might be considered first choice” by doctors, they write, although the two most effective drugs – amitriptyline and venlafaxine – might still be first choice for severe depression.
From The Guardian ● Feb. 21, 2018
Others have used low doses of tricyclic antidepressants, such as amitriptyline to treat chronic pain.
From US News ● May 24, 2016
Because amitriptyline interferes with sweating, your body cannot dissipate extra heat as it normally would.
From Seattle Times ● Aug. 1, 2012
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