[an-tee-koh-luh-nes-tuh-reys, -reyz, -kol-uh-, an-tahy-]
noun Biochemistry, Pharmacology.
  1. an enzyme or drug that blocks the action of acetylcholinesterase, thereby increasing the stimulating effect of acetylcholine on the muscles.

Origin of anticholinesterase

First recorded in 1950–55; anti- + cholinesterase Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for anticholinesterase


  1. any of a group of substances that inhibit the action of cholinesterase
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

anticholinesterase in Medicine


[ăn′tē-kō′lə-nĕstə-rās′, -rāz′, ăn′tī-]
  1. A substance that inhibits the activity of cholinesterases, including acetylcholinesterase.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.