[an-tee-koh-luh-nes-tuh-reys, -reyz, -kol-uh-, an-tahy-]

noun Biochemistry, Pharmacology.

an enzyme or drug that blocks the action of acetylcholinesterase, thereby increasing the stimulating effect of acetylcholine on the muscles.

Origin of anticholinesterase

First recorded in 1950–55; anti- + cholinesterase Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for anticholinesterase



any of a group of substances that inhibit the action of cholinesterase
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

anticholinesterase in Medicine


[ăn′tē-kō′lə-nĕstə-rās′, -rāz′, ăn′tī-]


A substance that inhibits the activity of cholinesterases, including acetylcholinesterase.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.