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cholinesterase

American  
[koh-luh-nes-tuh-reys, -reyz, kol-uh-] / ˌkoʊ ləˈnɛs təˌreɪs, -ˌreɪz, ˌkɒl ə- /

noun

Biochemistry.
  1. an enzyme, found especially in the heart, brain, and blood, that hydrolyzes acetylcholine to acetic acid and choline.


cholinesterase British  
/ ˌkɒl-, ˌkəʊlɪˈnɛstəˌreɪs /

noun

  1. an enzyme that hydrolyses acetylcholine to choline and acetic acid

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of cholinesterase

First recorded in 1930–35; choline + esterase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The cholinesterase inhibitors found in Navalny’s system reportedly block the breakdown of acetycholine, a vital chemical that transmits signals between nerve cells.

From Fox News Aug. 25, 2020

Atropine is the most common treatment for poisoning by a cholinesterase inhibitor.

From Washington Post Aug. 24, 2020

Specifically, the results were "highly suggestive" of something called cholinesterase inhibitor intoxication.

From BBC Sep. 20, 2019

The balance is very delicate indeed, and government veterinarians have found that repeated small doses can gradually deplete an animal’s supply of cholinesterase, so that without warning a minute additional dose will cause poisoning.

From The New Yorker Jan. 3, 2017

Repeated exposures may lower the cholinesterase level until an individual reaches the brink of acute poisoning, a brink over which he may be pushed by a very small additional exposure.

From "Silent Spring" by Rachel Carson

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