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cholinesterase

American  
[koh-luh-nes-tuh-reys, -reyz, kol-uh-] / ˌkoʊ ləˈnɛs təˌreɪs, -ˌreɪz, ˌkɒl ə- /

noun

Biochemistry.
  1. an enzyme, found especially in the heart, brain, and blood, that hydrolyzes acetylcholine to acetic acid and choline.


cholinesterase British  
/ ˌkəʊlɪˈnɛstəˌreɪs, ˌkɒl- /

noun

  1. an enzyme that hydrolyses acetylcholine to choline and acetic acid

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of cholinesterase

First recorded in 1930–35; choline + esterase

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

It said, however, that he was affected by a cholinesterase inhibitor, a chemical that blocks the transmission of impulses through the nervous system.

From Washington Post Aug. 25, 2020

The cholinesterase inhibitors found in Navalny’s system reportedly block the breakdown of acetycholine, a vital chemical that transmits signals between nerve cells.

From Fox News Aug. 25, 2020

Specifically, the results were "highly suggestive" of something called cholinesterase inhibitor intoxication.

From BBC Sep. 20, 2019

The balance is very delicate indeed, and government veterinarians have found that repeated small doses can gradually deplete an animal’s supply of cholinesterase, so that without warning a minute additional dose will cause poisoning.

From The New Yorker Jan. 3, 2017

A protective enzyme called cholinesterase is at hand to destroy the transmitting chemical once it is no longer needed.

From "Silent Spring" by Rachel Carson

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