Dictionary.com
Thesaurus.com

choline

American  
[koh-leen, kol-een] / ˈkoʊ lin, ˈkɒl in /

noun

  1. Biochemistry. a quaternary ammonium cation, C 5 H 14 N + O, one of the B-complex vitamins, found in the lecithin of many plants and animals.

  2. choline hydroxide, C 5 H 15 NO 2 , the viscous, strongly alkaline commercial form of this compound, usually synthesized, used as a feed supplement, especially for poultry, and in medicine in certain liver conditions.

  3. choline chloride, C 5 H 14 ClNO.


choline British  
/ ˈkəʊliːn, -ɪn, ˈkɒl- /

noun

  1. a colourless viscous soluble alkaline substance present in animal tissues, esp as a constituent of lecithin: used as a supplement to the diet of poultry and in medicine for preventing the accumulation of fat in the liver. Formula:[(CH 3 ) 3 NCH 2 CH 2 OH] + OH

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

choline Scientific  
/ kōlēn′ /
  1. A natural amine often classed in the vitamin B complex. It is incorporated into the structure of many other biologically important molecules, such as acetylcholine and lecithin. Chemical formula: C 5 H 15 NO 2 .


Etymology

Origin of choline

First recorded in 1855–60; chol- + -ine 2

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Even more striking, feeding the worms phosphatidylcholine or its precursor, choline, restored a more youthful mitochondrial structure within just two days.

From Science Daily Jun. 11, 2026

Norepinephrine is often elevated in anxiety disorders, and the UC Davis researchers suggest that this heightened arousal may increase the brain's demand for choline.

From Science Daily May 16, 2026

Maddock had previously seen low choline levels in studies of people with panic disorder.

From Science Daily May 16, 2026

Although the body can make a small amount on its own, most choline must come from food.

From Science Daily May 16, 2026

In another group of extracts from brain or nerve tissue, amino-ethanol H2NCH2CH2OH is found instead of the choline of lecithin.

From History of Phosphorus by Eduard Farber

Vocabulary.com logo
by dictionary.com

Dictionary.com's Learning Companion

Go beyond just looking up words.
Remember them forever with VocabTrainer.

Start training