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choline

American  
[koh-leen, kol-een] / ˈkoʊ lin, ˈkɒl in /

noun

  1. Biochemistry. a quaternary ammonium cation, C 5 H 14 N + O, one of the B-complex vitamins, found in the lecithin of many plants and animals.

  2. choline hydroxide, C 5 H 15 NO 2 , the viscous, strongly alkaline commercial form of this compound, usually synthesized, used as a feed supplement, especially for poultry, and in medicine in certain liver conditions.

  3. choline chloride, C 5 H 14 ClNO.


choline British  
/ ˈkəʊliːn, ˈkɒl-, -ɪn /

noun

  1. a colourless viscous soluble alkaline substance present in animal tissues, esp as a constituent of lecithin: used as a supplement to the diet of poultry and in medicine for preventing the accumulation of fat in the liver. Formula:[(CH 3 ) 3 NCH 2 CH 2 OH] + OH –

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

choline Scientific  
/ kō′lēn′ /
  1. A natural amine often classed in the vitamin B complex. It is incorporated into the structure of many other biologically important molecules, such as acetylcholine and lecithin. Chemical formula: C 5 H 15 NO 2 .


Etymology

Origin of choline

First recorded in 1855–60; chol- + -ine 2

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Even though the researchers expected to see reduced choline, the consistency of the result stood out.

From Science Daily ● May 16, 2026

That does not mean choline supplements are a proven treatment for anxiety.

From Science Daily ● May 16, 2026

The researchers think that chronic fight-or-flight activity may raise the brain's need for choline.

From Science Daily ● May 16, 2026

It also raises a larger question for future research: whether improving choline status could help restore brain chemistry in people with anxiety disorders.

From Science Daily ● May 16, 2026

Thus, Without the choline, lecithin would be a di-fatty acid derivative of glycero-phosphoric acid.

From The Chemistry of Plant Life by Roscoe Wilfred Thatcher

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