apolipoprotein

American  

[ap-uh-lip-uh-proh-teen, -tee-in, -lahy-puh-] / ˌæp əˌlɪp əˈproʊ tin, -ti ɪn, -ˌlaɪ pə- /

noun

Biochemistry.

1. the lipid-free protein portion of a lipoprotein.

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apolipoprotein British  

/ -ˌlaɪ-, ˌæpəˌlɪpəʊˈprəʊtiːn /

noun

1. any of a group of glycoproteins that form part of the structure of lipoproteins, some of which have been associated with Alzheimer's disease

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apolipoprotein Scientific  

/ ăp′ə-lĭp′ō-prō′tēn′,-lī′pō- /

1. Any of various proteins that combine with a lipid to form a lipoprotein, such as high density lipoprotein (HDL) and low density lipoprotein (LDL). Apolipoproteins are important in the transport of cholesterol in the body and the regulation of the level of cholesterol in cells and blood.

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Etymology

Origin of apolipoprotein

apo- + lipoprotein

Example Sentences

Testing for another protein, apolipoprotein B, can also be performed for those with high triglycerides, diabetes or other conditions, the guidelines say.

From The Wall Street Journal • Mar. 13, 2026

It picked up the well-known association between Alzheimer's and high cholesterol, through a variant form of the apolipoprotein E gene, APOE4.

From Science Daily • Feb. 21, 2024

In another experiment, we used the tau mouse model, which also expressed human APOE4, to test whether reducing levels of the apolipoprotein variant would protect against neurodegeneration.

From Scientific American • Jul. 26, 2021

This was a very important drug, says Corey, because its intended effects on apolipoprotein B and cholesterol were directly observed in humans.

From Nature • Oct. 15, 2019

Scientists are also looking at the apolipoprotein E3 and ApoE4 genes to explore genetic triggers.

From Washington Times • May 2, 2018