autophagy

American  

[aw-tah-fuhj-ee] / ɔˈtɑ fədʒ i /

noun

1. Cell Biology. the process by which a cell breaks down and reabsorbs parts of itself using enzymes it generates.

2. the act or process of consuming or digesting oneself.

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Other Word Forms

• autophagic adjective
• non-autophagic adjective

Example Sentences

The studies showed that chlorpyrifos disrupts autophagy, the cellular system responsible for clearing damaged proteins from cells.

From Science Daily

"By showing the biological mechanism in animal models, we've demonstrated that this association is likely causal. The discovery that autophagy dysfunction drives the neurotoxicity also points us toward potential therapeutic strategies to protect vulnerable brain cells."

From Science Daily

The discovery that chlorpyrifos interferes with autophagy highlights a possible target for future therapies aimed at protecting the brain from pesticide-related damage.

From Science Daily

Often described as 'geroprotectors,' they have been shown to stimulate autophagy, a cellular recycling process that clears out damaged components.

From Science Daily

"In normal tissues, eIF5A1, activated by polyamines, activates mitochondria via autophagy, whereas in cancer tissues, eIF5A2, whose synthesis is promoted by polyamines, controls gene expression at the translational level to facilitate the proliferation of cancer cells."

From Science Daily