baneful

He made some commonplace observation upon the baneful effect of the night air at the season.

It depresses the humble sufferer from its baneful effects; it irritates the passions of the unamiable.

That it was admirable as an organisation only shows it in a more baneful light, since it was used to crush out all progress.

Dangerfield had found a few hours rest in the morning, a rest broken by scurrying, baneful dreams.