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Pernicious anemia is an autoimmune condition characterized by poor absorption of which vitamin?

pernicious

American  
[per-nish-uhs] / pərˈnɪʃ əs /

adjective

  1. causing insidious harm or ruin; ruinous; injurious; hurtful.

    pernicious teachings;

    a pernicious lie.

    Synonyms:
    malicious, noxious, baneful, damaging, destructive, deleterious, detrimental, harmful
  2. deadly; fatal.

    a pernicious disease.

    Synonyms:
    lethal
  3. Obsolete. evil; wicked.


pernicious British  
/ pəˈnɪʃəs /

adjective

  1. wicked or malicious

    pernicious lies

  2. causing grave harm; deadly

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of pernicious

First recorded in 1515–25; from Latin perniciōsus “ruinous,” from pernici(ēs) “ruin” (from per- per- + -nici-, combining form of nex “death, murder” + -ēs, noun suffix) + -ōsus -ous

Explanation

Pernicious means harmful and subtle, such as a poison gas that causes illness in those exposed to it over the course of years. Pernicious comes from the Latin perniciosus, "destructive," which in turn comes from pernicies, "death" or "ruin." You might have heard your parents and teachers talk about the pernicious effects of watching too much TV and playing video games all day — they'll turn your brain to mush (allegedly).

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Vocabulary lists containing pernicious

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The professionalization of youth sports—the incursion of for-profit companies strip-mining American childhood—hasn’t only wiped out recreational sports, it’s created a pernicious money culture.

From The Wall Street Journal ● Aug. 20, 2026

Lender losses drive a contraction of credit availability, the lifeblood of modern economies, leading to slowing economic activity and driving further iterations of the pernicious cycle.

From MarketWatch ● Jul. 9, 2026

He said conversion practices could be "particularly pernicious" in a church setting.

From BBC ● Jul. 4, 2026

In 2026, it is 100 years since George Minot and William Murphy reported that a liver-rich diet could treat pernicious anemia, then a frequently fatal disease.

From Science Daily ● Jun. 25, 2026

Something deeper, more pernicious was at work here: a wide division between the wealthy and the poor that was made worse by fear.

From "The Great Fire" by Jim Murphy

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