base editing

American  

[bays ed-it-ing] / ˈbeɪs ˌɛd ɪt ɪŋ /

noun

1. Genetics. a precise gene editing technique in which a single base or nucleotide (represented by a letter) is replaced by another in the sequence of a piece of DNA.

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Other Word Forms

• base editor
  noun
• base-edited
  adjective

Example Sentences

See Examples For:

base editing

The technology Egli’s group used, called base editing, allows them to target individual DNA letters in sequences more precisely with fewer adverse effects.

From The Wall Street Journal ● Jun. 5, 2026

A DNA-editing technique, base editing, was used on early-stage embryos to fix disease-causing mutations.

From The Wall Street Journal ● Jun. 5, 2026

With base editing, developed in 2016, researchers can engineer point mutations, but not all possible point mutations.

From Science Daily ● Mar. 12, 2024

Dr David Liu, one of the inventors of base editing at the Broad Institute, told me it was "a bit surreal" that people were being treated just six years after the technology was invented.

From BBC ● Dec. 10, 2022

Seidman says the team is encouraged by a recent success at using DNA base editing to repair heart cells and other kinds in mice with progeria, a disease that causes children to age rapidly.

From Science Magazine ● Jul. 28, 2022