be the end of one

1. Be one's downfall, as in His heavy drinking may well be the end of him, or That math assignment will be the end of me. This phrase originally alluded to something that would cause someone's death. Today, while it may be used seriously (as in the first example), it more often is used more lightly (as in the second).

Example Sentences

Mr. Carlson’s and Mr. Lemon's exits may be the end of one era in cable news.

Read more on New York Times

Will Nevada be the end of one of the six main candidates?

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This could be the end of one of the greatest stretches of quarterback play the NFL has seen.

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It will be the end of one era just as Rosen continues the early stages of what he hopes is a lengthy professional football career.

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Some remain sceptical, given previous frequent rumours of closure that have come to nothing, but if Butyrka does close it will be the end of one of the most storied and feared prisons in the world.

Read more on The Guardian