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Benadryl

American  
[ben-uh-dril] / ˈbɛn ə drɪl /
Pharmacology, Trademark.
  1. a brand of diphenhydramine.


Benadryl British  
/ ˈbɛnədrɪl /

noun

  1. an antihistamine drug used in sleeping tablets; diphenhydramine. Formula: C 17 H 21 NO

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Example Sentences

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See Examples For:

Sales rose 1.5% in Kenvue’s self care business, which includes products such as Tylenol and Benadryl.

From The Wall Street Journal Feb. 17, 2026

If you’re highly allergic to mosquitoes, the American Mosquito Control Assn. said you may need a cream with Benadryl or a similar antihistamine.

From Los Angeles Times Jul. 29, 2024

Classic brand names like Benadryl, Claritin, Allegra, and Zyrtec are antihistamines, which can be used to treat, or lessen, that histamine reaction and thus the itch.

From Slate Sep. 23, 2023

If the F.D.A. ordered their removal, a trade group warned that numerous popular products — including Tylenol, Mucinex and Benadryl cold and flu remedies — might become unavailable as companies race to reformulate them.

From New York Times Sep. 12, 2023

So is redness and swelling, which could explain why her red welts didn’t go away despite all the Benadryl she drank.

From "The Immortal Life of Henrietta Lacks" by Rebecca Skloot

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