Dictionary.com
Thesaurus.com

Benadryl

American  
[ben-uh-dril] / ˈbɛn ə drɪl /
Pharmacology, Trademark.
  1. a brand of diphenhydramine.


Benadryl British  
/ ˈbɛnədrɪl /

noun

  1. an antihistamine drug used in sleeping tablets; diphenhydramine. Formula: C 17 H 21 NO

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Anticholinergics also include diphenhydramine, the active ingredient in over-the-counter products like Benadryl.

From The Wall Street Journal Jan. 8, 2026

If you’re highly allergic to mosquitoes, he said, you may need a cream with Benadryl or similar antihistamine.

From Los Angeles Times Feb. 14, 2024

At issue is phenylephrine, an almost-century-old ingredient in versions of Benadryl, Mucinex, Tylenol and other over-the-counter pills, syrups and liquids to clear up congested noses.

From Slate Sep. 13, 2023

If the F.D.A. ordered their removal, a trade group warned that numerous popular products — including Tylenol, Mucinex and Benadryl cold and flu remedies — might become unavailable as companies race to reformulate them.

From New York Times Sep. 12, 2023

The whole episode—including anti-itch cream, prednisone, prednisone cream, and Benadryl to get through the nights—eats up $30.

From "Nickel and Dimed: On (Not) Getting By in America" by Barbara Ehrenreich

Vocabulary.com logo
by dictionary.com

Dictionary.com's Learning Companion

Go beyond just looking up words.
Remember them forever with VocabTrainer.

Start training