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bioavailability

American  
[bahy-oh-uh-vey-luh-bil-i-tee] / ˌbaɪ oʊ əˌveɪ ləˈbɪl ɪ ti /

noun

Biochemistry.
  1. the extent to which a nutrient or medication can be used by the body.


bioavailability British  
/ ˌbaɪəʊəˌveɪləˈbɪlɪtɪ /

noun

  1. Also called: systemic availability.  the extent to which a drug or other substance is taken up by a specific tissue or organ after administration; the proportion of the dose of a drug that reaches the systemic circulation intact after administration by a route other than intravenous

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of bioavailability

First recorded in 1965–70; bio- + available ( def. )

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

It achieved a pharmacological bioavailability of about 33-41% compared to subcutaneous injection.

From Science Daily • Mar. 24, 2026

“Systemic therapies have shown poor bioavailability in pancreatic tumors, limiting their effectiveness. Optune Pax is a fundamentally different treatment, utilizing a biophysical approach that targets the unique electrical properties of cancer cells.”

From Barron's • Feb. 12, 2026

“If you take it orally, the bioavailability is in the range of 4–6%, which is terrible,” says Devinsky.

From Nature • Aug. 27, 2019

Ratain said food can increase or decrease the absorption rate, or bioavailability, of some drugs.

From Washington Post • Jun. 8, 2017

Bioequivalence studies measure whether a generic drug acts the same in the body as the name-brand drug; bioavailability studies measure how much drug gets into a patient’s system.

From Salon • Apr. 17, 2013

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