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Synonyms

breakthrough

American  
[breyk-throo] / ˈbreɪkˌθru /

noun

  1. a military movement or advance all the way through and beyond an enemy's frontline defense.

  2. an act or instance of removing or surpassing an obstruction or restriction; the overcoming of a stalemate.

    The president reported a breakthrough in the treaty negotiations.

  3. any significant or sudden advance, development, achievement, or increase, as in scientific knowledge or diplomacy, that removes a barrier to progress.

    The jet engine was a major breakthrough in air transport.

  4. Medicine/Medical. an infection, disease, disorder, or condition that occurs in an individual despite their having received a vaccine, medication, or treatment.

    Covid breakthroughs are usually less severe than infections in unvaccinated people, indicating that the vaccine is still doing its job of combating the virus.


adjective

  1. constituting a breakthrough: Critics called it a breakthrough film.

    Their products are engineered with breakthrough technology.

    Critics called it a breakthrough film.

  2. Medicine/Medical. relating to or being an infection, disease, disorder, or condition that occurs as a breakthrough: She experienced disabling breakthrough pain despite the high dose of painkillers she was taking.

    In the original vaccine trial, 89% of breakthrough infections were with a particular family of virus strains.

    She experienced disabling breakthrough pain despite the high dose of painkillers she was taking.

Etymology

Origin of breakthrough

First recorded in 1915–20; noun use of verb phrase break through

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Earlier this year, the Bronx-born Dominican actor reprised her breakthrough TV role as Carla Espinosa on the reboot of the beloved ABC medical sitcom, “Scrubs.”

From Los Angeles Times • Mar. 31, 2026

PrismML has achieved a mathematical breakthrough that achieves a 1-bit model without compromising the reasoning, coding, and general knowledge capabilities of full-precision models, according to Hassibi.

From The Wall Street Journal • Mar. 31, 2026

Parents have described the breakthrough as "incredibly meaningful" and a starting point for better treatment and understanding of the condition.

From BBC • Mar. 30, 2026

Beyond its size, the breakthrough could have major implications for long-term data storage.

From Science Daily • Mar. 29, 2026

When word of the breakthrough in making sugar reached the landowners in that one more advanced part of Russia, they knew just what to do: plant beets.

From "Sugar Changed the World: A Story of Magic, Spice, Slavery, Freedom, and Science" by Marc Aronson