cell membrane
Americannoun
noun
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The thin membrane that forms the outer surface of the protoplasm of a cell and regulates the passage of materials in and out of the cell. It is made up of proteins and lipids and often contains molecular receptors. The membranes of organelles within the cell are made of the same basic material as the cell membrane. In plant cells, the cell membrane is surrounded by a rigid cell wall.
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Also called plasma membrane
Usage
What is a cell membrane? The cell membrane is the thin layer that encloses a cell’s cytoplasm, which is the substance between the membrane and the nucleus. It allows beneficial things to pass through while blocking harmful ones.The cell is the basic structural unit of all living organisms. It is a microscopic structure consisting of a nucleus surrounded by the cytoplasm and enclosed by a membrane—the cell membrane. In general, a membrane is a thin barrier or covering.The membrane consists of a double layer made up of lipid molecules and large protein molecules. Lipids and proteins are the basic building blocks of living cells. They move fluidly in the cell membrane and function like a system of gates, giving the membrane its ability to allow molecules to pass through. For this reason, the membrane is described as semipermeable (meaning it is capable of allowing things to pass through it).Plants cells also have a rigid outer wall in addition to a cell membrane.The cell membrane is also called the plasma membrane or the plasmalemma.
Etymology
Origin of cell membrane
First recorded in 1865–70
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Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
By engaging receptor trafficking at the cell membrane, they provide a new way to modulate receptor activity.
From Science Daily • Oct. 30, 2025
Finally, the potassium-to-sodium ratio reflects the natural function of cell membrane pumps, which concentrate potassium inside cells while transporting sodium out.
From Salon • Dec. 30, 2024
They then examined the hemagglutinin proteins, or spikes, on the outer surface of the virus, since those enable it to latch onto the cell membrane of its host.
From Los Angeles Times • Dec. 5, 2024
One unexpected discovery was that a snoRNA called SNORA73 interacts with mRNAs that encode secreted proteins and cell membrane proteins.
From Science Daily • Nov. 22, 2024
We may be able to treat germ cells with acids or other substances which destroy the cell membrane so as to allow crossing between very widely separated species and genera.
From Northern Nut Growers Association, Report of the Proceedings at the Third Annual Meeting Lancaster, Pennsylvania, December 18 and 19, 1912 by Northern Nut Growers Association
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.