ceramide

/ ˈsɛrəˌmaɪd /

noun

1. any of a class of biologically important compounds used as moisturizers in skin-care preparations

Example Sentences

"Ceramide levels are very elevated in kidney injury," says Rebekah Nicholson, PhD, first author on the work, who completed the research as a graduate student in nutrition and integrative physiology at U of U Health and is now a postdoctoral fellow at the Arc Institute.

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"They go up quickly after damage to the kidneys, and they go up in relation to the severity of the injury. The worse the kidney injury is, the higher the ceramide levels will be."

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The team nearly eliminated kidney injury in a mouse model by modifying the genetic program that controls ceramide production.

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Adjusting ceramide production, whether genetically or with the drug, kept mitochondria intact and working even under strain.

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In their model, however, the researchers observed that while ceramide levels were high in the bloodstream, levels in artery-lining endothelial cells remained about the same regardless of coronary artery disease status.

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