[ kal-ohn ]
/ ˈkæl oʊn /

noun Physiology.

an endocrine secretion that depresses or inhibits physiological activity.

Origin of chalone

1910–15; < Greek chalôn, present participle of chalân to slacken, loosen; on the model of hormone Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2019

British Dictionary definitions for chalone

/ (ˈkæləʊn) /


any internal secretion that inhibits a physiological process or function

Word Origin for chalone

C20: from Greek khalōn, from khalan to slacken
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medicine definitions for chalone

[ kālōn′, kălōn′ ]


A hormone that inhibits rather than stimulates.
Any of several polypeptides produced by a tissue and causing the reversible inhibition of mitosis in cells of that tissue.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.