chlorambucil

American

[klaw-ram-byuh-sil, kloh-] / klɔˈræm byə sɪl, kloʊ- /

noun

Pharmacology.

a nitrogen mustard, C 14 H 19 Cl 2 NO 2 , used in the treatment of chronic lymphocytic leukemia, malignant lymphomas, and Hodgkin's disease.

chlorambucil British

/ klɔːˈræmbjʊsɪl /

noun

an alkylating drug derived from nitrogen mustard, administered orally in the treatment of leukaemia and other malignant diseases. Formula: C 14 H 19 Cl 2 NO 2

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Etymology

Origin of chlorambucil

1955–60; chlor(oethyl) + am(inophen) + bu(tyric acid), components of the chemical name + -cil of uncertain derivation

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In the 663-patient study, patients who received Gazyva plus the chemotherapy drug chlorambucil on average went 26.7 months without their disease worsening, a measure known as progression free survival, or PFS.

From Reuters • Nov. 7, 2013

That compared with 15.2 months for previously untreated patients who took Rituxan and chlorambucil, according to data announced by the Swiss company on Thursday.

From Reuters • Nov. 7, 2013

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023