cinchonine

American  

[sing-kuh-neen, -nin, sin-] / ˈsɪŋ kəˌnin, -nɪn, ˈsɪn- /

noun

Pharmacology.

1. a colorless, crystalline, slightly water-soluble alkaloid, C 19 H 22 N 2 O, a stereoisomer of cinchonidine, obtained from the bark of various species of cinchona and used chiefly as a quinine substitute.

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cinchonine British  

/ ˈsɪŋkəˌniːn /

noun

1. an insoluble crystalline alkaloid isolated from cinchona bark, used to treat malaria. Formula: C 19 H 22 N 2 O

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Etymology

Origin of cinchonine

First recorded in 1815–25; cinchon(a) + -ine ²

Example Sentences

See Examples For:

cinchonine

Quinidine is almost as powerful an antidote to malaria as quinine; cinchonidine has about two-thirds the power of quinine, and cinchonine less than one-half.

From Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 3 "Chitral" to "Cincinnati" by Various

This base was discovered in coal-tar by Runge in 1834, and was obtained by Gerhardt in 1842 by distilling cinchonine, one of the cinchona alkaloïds, with alkali.

From Coal and What We Get from It by Meldola, Raphael

Cinchonidine, when heated with potassium hydrate, yields quinoline also, and with nitric acid the same products as cinchonine.

From Scientific American Supplement, No. 415, December 15, 1883 by Various

When cinchonine is treated with potassium hydrate, it is decomposed into quinoline and a solid body, which on further treatment yields a liquid base, C7H9N, which is probably lutidine.

From Scientific American Supplement, No. 415, December 15, 1883 by Various

Their great value depends upon the presence of certain alkaloid substances called quinine, cinchonine, and quinidine, which exist in the bark in combination with tannic and other acids.

From Catalogue of Economic Plants in the Collection of the U. S. Department of Agriculture by Saunders, William