cinchonine

American  

[sing-kuh-neen, -nin, sin-] / ˈsɪŋ kəˌnin, -nɪn, ˈsɪn- /

noun

Pharmacology.

1. a colorless, crystalline, slightly water-soluble alkaloid, C 19 H 22 N 2 O, a stereoisomer of cinchonidine, obtained from the bark of various species of cinchona and used chiefly as a quinine substitute.

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cinchonine British  

/ ˈsɪŋkəˌniːn /

noun

1. an insoluble crystalline alkaloid isolated from cinchona bark, used to treat malaria. Formula: C 19 H 22 N 2 O

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Etymology

Origin of cinchonine

First recorded in 1815–25; cinchon(a) + -ine ²

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Example Sentences

See Examples For:

cinchonine

It is stated that incomplete examinations have detected cinchonine in the bark.

From Catalogue of Economic Plants in the Collection of the U. S. Department of Agriculture by William Saunders

Cinchonidine, when heated with potassium hydrate, yields quinoline also, and with nitric acid the same products as cinchonine.

From Scientific American Supplement, No. 415, December 15, 1883 by Various

When cinchonine is distilled with solid potassium hydrate, it yields pyrrol and bases of both the pyridine and quinoline series.

From Scientific American Supplement, No. 415, December 15, 1883 by Various

Quinidine is almost as powerful an antidote to malaria as quinine; cinchonidine has about two-thirds the power of quinine, and cinchonine less than one-half.

From Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 3 "Chitral" to "Cincinnati" by Various

A fourth alkaloid, cinchonidine, is isomeric with cinchonine, which yields it when boiled with amyl alcoholic potash, but is laevo-rotatory, slightly soluble in ether, and faintly fluorescent.

From Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 3 "Chitral" to "Cincinnati" by Various

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