cisplatin

American  

[sis-plat-n] / sɪsˈplæt n /

Also cisplatinum

noun

Pharmacology.

1. a platinum-containing white powder, PtCl 2 H 6 N 2 , used to treat ovarian carcinoma and other cancers.

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cisplatin British  

/ sɪsˈplætɪn /

noun

1. a cytotoxic drug that acts by preventing DNA replication and hence cell division, used in the treatment of tumours, esp of the ovary and testis

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cisplatin Scientific  

/ sĭs-plā′tn /

1. A platinum-containing chemotherapeutic drug used in the treatment of metastatic ovarian or testicular cancers and advanced bladder cancer. Chemical formula: Cl ₂ H ₆ N ₂ Pt.

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Etymology

Origin of cisplatin

First recorded in 1975–80; cis- + platin(um)

Example Sentences

Bhargava said this highly targeted approach minimizes the toxic side effects seen with the platinum-based cisplatin, which targets DNA and damages both healthy and cancerous cells.

From Science Daily • Nov. 27, 2024

Jeff Bolle, 60, died on Dec. 29, 2023 of stage 4 bile duct cancer, seven months after his last chemotherapy treatment with a drug known as cisplatin.

From Salon • May 3, 2024

The mutations mimic damage from noise, aging or drugs like cisplatin.

From Science Daily • Jan. 8, 2024

The dearth of drugs such as carboplatin or cisplatin, used in treating cancer, can be linked in part to quality issues at a major plant in India late last year.

From Washington Times • Dec. 26, 2023

Two of these drugs, carboplatin and cisplatin, are inexpensive and are used to treat up to 20 percent of cancer patients, according to the National Institutes of Health.

From New York Times • Dec. 19, 2023