cisplatin

American  

[sis-plat-n] / sɪsˈplæt n /

Also cisplatinum

noun

Pharmacology.

1. a platinum-containing white powder, PtCl 2 H 6 N 2 , used to treat ovarian carcinoma and other cancers.

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cisplatin British  

/ sɪsˈplætɪn /

noun

1. a cytotoxic drug that acts by preventing DNA replication and hence cell division, used in the treatment of tumours, esp of the ovary and testis

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cisplatin Scientific  

/ sĭs-plā′tn /

1. A platinum-containing chemotherapeutic drug used in the treatment of metastatic ovarian or testicular cancers and advanced bladder cancer. Chemical formula: Cl ₂ H ₆ N ₂ Pt.

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Etymology

Origin of cisplatin

First recorded in 1975–80; cis- + platin(um)

Example Sentences

In mice studies, the gold compound reduced cervical cancer tumour growth by 82%, compared to cisplatin's 29%.

From Science Daily

Bhargava said this highly targeted approach minimizes the toxic side effects seen with the platinum-based cisplatin, which targets DNA and damages both healthy and cancerous cells.

From Science Daily

This included ovarian cancer cells, which are known to develop resistance to cisplatin treatment in many cases.

From Science Daily

Jeff Bolle, 60, died on Dec. 29, 2023 of stage 4 bile duct cancer, seven months after his last chemotherapy treatment with a drug known as cisplatin.

From Salon

After undergoing surgery and four rounds of chemotherapy, Bolle's treatments were stopped in May of 2023 when cisplatin became unavailable.

From Salon