cisplatin

Also cis·plat·i·num

[sis-plat-n]

noun

Pharmacology.

1. a platinum-containing white powder, PtCl 2 H 6 N 2 , used to treat ovarian carcinoma and other cancers.

cisplatin

/ sɪsˈplætɪn /

noun

1. a cytotoxic drug that acts by preventing DNA replication and hence cell division, used in the treatment of tumours, esp of the ovary and testis

cisplatin

1. A platinum-containing chemotherapeutic drug used in the treatment of metastatic ovarian or testicular cancers and advanced bladder cancer. Chemical formula: Cl ₂ H ₆ N ₂ Pt.

Word History and Origins

Origin of cisplatin¹

First recorded in 1975–80; cis- + platin(um)

Word History and Origins

Origin of cisplatin¹

C20: from _cis- + _platin ( _um )

Example Sentences

In mice studies, the gold compound reduced cervical cancer tumour growth by 82%, compared to cisplatin's 29%.

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Bhargava said this highly targeted approach minimizes the toxic side effects seen with the platinum-based cisplatin, which targets DNA and damages both healthy and cancerous cells.

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This included ovarian cancer cells, which are known to develop resistance to cisplatin treatment in many cases.

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Jeff Bolle, 60, died on Dec. 29, 2023 of stage 4 bile duct cancer, seven months after his last chemotherapy treatment with a drug known as cisplatin.

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After undergoing surgery and four rounds of chemotherapy, Bolle's treatments were stopped in May of 2023 when cisplatin became unavailable.

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