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  • cis
    cis
    adjective
    cisgender or cissexual.
  • cis-
    cis-
    a prefix occurring in loanwords from Latin meaning “on the near side of; on this side of” (cisalpine ); on this model, used in the formation of compound words (cisatlantic ).
  • C.I.S.
    C.I.S.
    abbreviation
    Commonwealth of Independent States.
  • CIS
    CIS
    abbreviation
    Commonwealth of Independent States
SEE ALSO:
Gender & Sexuality dictionary results for cis.

cis

1 American  
[sis] / sɪs /

adjective

  1. cisgender or cissexual.

    He may not be macho, but he's definitely a cis male.


noun

  1. a person who is cisgender or cissexual.

cis- 2 American  
  1. a prefix occurring in loanwords from Latin meaning “on the near side of; on this side of” (cisalpine ); on this model, used in the formation of compound words (cisatlantic ).

  2. Chemistry. a specialization of this denoting a geometric isomer having a pair of identical atoms or groups attached on the same side of two atoms linked by a double bond.

  3. a prefix meaning “on the same side of,” referring to the alignment of one’s gender identity with one’s sex assigned at birth (cisgender; cissexual ).


C.I.S. 3 American  

abbreviation

  1. Commonwealth of Independent States.


cis- 1 British  

prefix

  1. on this or the near side of

    cisalpine

  2. (often in italics) indicating that two groups of atoms in an unsaturated compound lie on the same side of a double bond Compare trans-

    cis-butadiene

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

CIS 2 British  

abbreviation

  1. Commonwealth of Independent States

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Sensitive Note

See trans, gender 1.

Usage

What does cis mean? Cis is short for cissexual or, more commonly, cisgender, which refers to someone's gender identity that corresponds to their sex as assigned at birth. Cisgender is the opposite of transgender.

Etymology

Origin of cis1

By shortening

Origin of cis-2

From Latin cis (adverb and preposition) “on this side, on this side of, within”

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The agency also sought to get testosterone therapy to more cis men in order to help boost their libido.

From Salon May 13, 2026

“It treats transgender women differently than cis women.”

From The Wall Street Journal Jan. 13, 2026

I am entirely aware that my ability to be fully myself on a dating app is a luxury afforded to me by my status as a cis, straight, thin, white woman in New York City.

From Slate Jan. 7, 2026

"This has even resulted in cis women being challenged for going into a female toilet because they have a short haircut," the statement added.

From BBC May 14, 2025

“And I dunno. Being attracted to someone not cis makes me think I could be attracted to someone nonbinary. Which is why I’m not sure ‘bisexual’ is the right word, at least for me.

From "Odd One Out" by Nic Stone

During this hydrogenation process, double bonds in the cis- conformation in the hydrocarbon chain may be converted to double bonds in the trans- conformation; unfortunately, trans fats have been shown to contribute to heart disease.

From Textbooks Jun. 9, 2022

During this hydrogenation process, double bonds of the cis- conformation in the hydrocarbon chain may be converted to double bonds in the trans- conformation.

From Textbooks Jun. 9, 2022

Molecules must have a single bond to be cis- trans isomers.

From Textbooks Jun. 9, 2022

Collectively, our work provides insights into the complex cis- and trans-regulation of A-to-I editing.

From Nature Oct. 10, 2017

Single, highly-favoured individuals, not only in England but in other countries cis- and trans-Atlantic, enjoy incomes equal to more than half the amount of Elizabeth's annual budget.

From History of the United Netherlands from the Death of William the Silent to the Twelve Year's Truce, 1585e by Motley, John Lothrop

Five of the 11 leaders invited to the most recent C.I.S. summit meeting failed even to show, and the leading Azeri presidential candidate last week declared his intention to withdraw Azerbaijan from the Commonwealth entirely.

From Time Magazine Archive

Nursultan Nazarbayev, President of Kazakhstan, warns that the clash may "create a precedent for uncontrolled development of conflicts within the C.I.S."

From Time Magazine Archive

"One standard of C.I.S. conduct should be a stand-down on intelligence gathering," argues Paul Joyal, a former U.S.

From Time Magazine Archive

Meanwhile, C.I.S. leaders elected the Russian President to another year as head of the alliance.

From Time Magazine Archive

Shaposhnikov's fears may be exaggerated, but the utter failure of the C.I.S. to mediate even a temporary cease-fire in Karabakh suggests that the Commonwealth may go the way of its Soviet predecessor.

From Time Magazine Archive

Lyle Ungar, Professor in CIS and a co-author of the study, says social media can offer insight into concerns patients may not always bring up during medical visits.

From Science Daily May 24, 2026

Risks, however, include debates on the durability of the company’s CIS growth and how it can remain competitive against hyperscalers.

From Barron's May 13, 2026

Some companies import European cheese to Belarus or other CIS countries, where the label is swapped so that it can be sold legally in Russian shops.

From BBC Nov. 10, 2024

It was only the second time that Sumar appeared in a CIS poll after racking up 10.6% of voting intentions last month.

From Reuters May 17, 2023

Many Western academic institutions, NGO's, and commercial interests created frameworks for collaboration with space scientists from Central Asia, Central and Eastern Europe, Russia, CIS, and NIS.

From Russian Roulette: Russia's Economy in Putin's Era by Vaknin, Samuel

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