cisplatin

American  

[sis-plat-n] / sɪsˈplæt n /

Also cisplatinum

noun

Pharmacology.

1. a platinum-containing white powder, PtCl 2 H 6 N 2 , used to treat ovarian carcinoma and other cancers.

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cisplatin British  

/ sɪsˈplætɪn /

noun

1. a cytotoxic drug that acts by preventing DNA replication and hence cell division, used in the treatment of tumours, esp of the ovary and testis

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cisplatin Scientific  

/ sĭs-plā′tn /

1. A platinum-containing chemotherapeutic drug used in the treatment of metastatic ovarian or testicular cancers and advanced bladder cancer. Chemical formula: Cl ₂ H ₆ N ₂ Pt.

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Etymology

Origin of cisplatin

First recorded in 1975–80; cis- + platin(um)

Example Sentences

After undergoing surgery and four rounds of chemotherapy, Bolle's treatments were stopped in May of 2023 when cisplatin became unavailable.

From Salon • May 3, 2024

After three weeks, mice that received cisplatin but not gamma therapy showed many of the expected effects of chemotherapy: brain volume shrinkage, DNA damage, demyelination, and inflammation.

From Science Daily • Mar. 6, 2024

The dearth of drugs such as carboplatin or cisplatin, used in treating cancer, can be linked in part to quality issues at a major plant in India late last year.

From Washington Times • Dec. 26, 2023

Two of these drugs, carboplatin and cisplatin, are inexpensive and are used to treat up to 20 percent of cancer patients, according to the National Institutes of Health.

From New York Times • Dec. 19, 2023

They also found evidence that TcdBFBD can synergize with the standard chemotherapy drug cisplatin to inhibit both basal-like and luminal-like breast cancer tumors in mice.

From Science Daily • Nov. 9, 2023