constant region

American  

noun

1. Immunology. the part of the polypeptide sequence in a heavy or light chain of an antibody forming the C-terminal portion of the chain and is the same for all members of the class it specifies. Compare variable region.

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constant region Scientific  

1. The portion of the amino acid sequence of an antibody's heavy or light chains that determines the class of the antibody and does not vary within a given class. The constant region terminates in a free carboxyl group (COOH). Unlike the variable region, the constant region does not interact with antigens.

2. Compare variable region

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Example Sentences

In Traverse City, the ever-tightening housing market provides a constant weight against advocates who work toward lifting those who struggle most.

From Washington Times • Dec. 28, 2020

In constant weight freediving, divers cannot use supplementary weights to aid their descent and can touch only the dive line used to guide them when turning around to begin their ascent.

From Washington Post • Nov. 13, 2020

Pro 950GH hit the market as the first constant weight steel shaft less than 100 grams.

From Golf Digest • Aug. 28, 2019

“It feels like a constant weight is just sitting on my chest, making it impossible to take a full breath,” she said.

From Reuters • Aug. 21, 2018

In all cases ignition should be to constant weight so as to insure complete decomposition of carbonates.

From Soap-Making Manual A Practical Handbook on the Raw Materials, Their Manipulation, Analysis and Control in the Modern Soap Plant. by Thomssen, E. G.