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cross-tolerance

American  
[kraws-tol-er-uhns, kros-] / ˈkrɔsˈtɒl ər əns, ˈkrɒs- /

noun

Physiology.

  1. the resistance to one or more effects of a substance because of tolerance to a pharmacologically similar substance.

    a cross-tolerance of some alcoholics to anesthetics.

Etymology

Origin of cross-tolerance

First recorded in 1920–25

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023

Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.

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