Cushing's disease

American  

noun

Pathology.

1. a disease characterized by abnormal accumulations of facial and trunk fat, fatigue, hypertension, and osteoporosis, caused by hyperfunction of the adrenal cortex or administration of adrenal cortical hormones.

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Cushing's disease British  

/ ˈkʊʃɪŋz /

noun

1. a rare condition caused by excess corticosteroid hormones in the body, characterized chiefly by obesity of the trunk and face, high blood pressure, fatigue, and loss of calcium from the bones

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Etymology

Origin of Cushing's disease

1935–40; after H. W. Cushing, who first described it

Example Sentences

Doctors routinely prescribe them for miscarriage management, endometriosis, fibroids, complications from Cushing’s disease and other serious reproductive health conditions, where they can prevent infection or reduce severe pain.

From Salon • May 2, 2026

Later, her sister was diagnosed with Cushing’s disease.

From Washington Post • Jan. 20, 2022

His mother would die, from complications due to Cushing’s disease, in 2008.

From The New Yorker • Dec. 10, 2018

Ms Matthews, who grew up in Herefordshire but now lives in London, was diagnosed with Cushing's disease in 2009.

From BBC • Mar. 23, 2018

Other common signs of Cushing’s disease include the development of a moon-shaped face, a buffalo hump on the back of the neck, rapid weight gain, and hair loss.

From Textbooks • Jun. 19, 2013