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  • cyst
    cyst
    noun
    a closed, bladderlike sac formed in animal tissues, containing fluid or semifluid matter.
  • cyst-
    cyst-
    variant of cysto-, before a vowel.
  • -cyst
    -cyst
    variant of cysto-, as final element in a compound word.
Synonyms

cyst

1 American  
[sist] / sɪst /

noun

cysts plural
  1. Pathology. a closed, bladderlike sac formed in animal tissues, containing fluid or semifluid matter.

  2. a bladder, sac, or vesicle.

  3. Botany, Mycology.

    1. a sporelike cell with a resistant, protective wall.

    2. a cell or cavity enclosing reproductive bodies.

  4. Zoology.

    1. a sac, usually spherical, surrounding an animal that has passed into a dormant condition.

    2. such a sac plus the contained animal.

    3. a capsule or resistant covering.


cyst- 2 American  
  1. variant of cysto-, before a vowel.

    cystectomy.


-cyst 3 American  
  1. variant of cysto-, as final element in a compound word.

    statocyst.


-cyst 1 British  

combining form

  1. indicating a bladder or sac

    otocyst

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

cyst 2 British  
/ sɪst /

noun

  1. pathol any abnormal membranous sac or blisterlike pouch containing fluid or semisolid material

  2. anatomy any normal sac or vesicle in the body

  3. a thick-walled protective membrane enclosing a cell, larva, or organism

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

cyst Scientific  
/ sĭst /
  1. An abnormal membranous sac in the body, containing a gaseous, liquid, or semisolid substance.

  2. A small, capsulelike form of certain organisms that develops in response to adverse or extreme conditions. Under adverse conditions, for instance, dinoflagellates form nonmotile resting cysts that fall to the ocean or lake bottom and can remain there for years before reviving. Certain invertebrates, such as the water bear (phylum Tardigrada), also develop cysts.


cyst Cultural  
  1. An abnormal saclike structure that develops in the body and is filled with fluid or semisolid material.


Usage

What does cyst- mean? The combining form cyst- is a combining form used like a suffix meaning “cyst,” which is a scientific term for a bladder, sac, or vesicle. It is often used in scientific terms, especially in biology and pathology. The form cyst- comes from Greek kýstis, meaning “bag,” “pouch,” or “bladder.”What are variants of cyst-?The form cyst- is a variant of cysto-, which loses its -o- when combined with words or word elements beginning with vowels. A rare variant of cysto- is cysti-, as in cystiform. When used as a suffix, the combining form cyst- becomes -cyst, as in oocyst. Want to know more? Read our Words That Use articles for these forms.

What does -cyst mean? The combining form -cyst is used like a suffix meaning “cyst,” which is a scientific term for a bladder, sac, or vesicle. It is often used in scientific terms, especially in biology. The form -cyst comes from Greek kýstis, meaning “bag,” “pouch,” or “bladder.”What are variants of -cyst?When used as a prefix, the combining form -cyst variously becomes cyst-, cysti-, or cysto- (as in cystoma). Want to know more? Read our Words That Use articles for these forms.

Other Word Forms

Noun Inflected Forms

Etymology

Origin of cyst

First recorded in 1705–15; from New Latin cystis, from Greek kýstis “bag, pouch, bladder”; akin to kŷma cyma

Explanation

A cyst is a small growth that forms in the body. That squishy, fluid-filled mass on your calf could be a cyst. The word cyst entered English in the 18th century by way of the Latin word cystis, tracing all the way back to the Greek word kustis, meaning “bladder.” Like your bladder, a cyst is sort of like a small pouch, one that’s typically filled with liquid. Unlike the bladder, however, a cyst is closed, meaning the liquid can’t get out. A cyst is often an abnormal formation in the body, so doctors often remove them.

Keep Reading on Vocabulary.com

Vocabulary lists containing cyst

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The drug works by blocking vasopressin, which helps reduce cyst growth.

From Science Daily Jun. 17, 2026

Ueda is expected to remain in the hospital for about two weeks while receiving treatment for an infected liver cyst, the central bank said.

From The Wall Street Journal Jun. 12, 2026

She said: "The pain started to become a daily thing after my ovarian cyst ruptured and then my mobility started to be affected and I couldn't work."

From BBC Mar. 23, 2026

During a recent health crisis, an emergency surgery to remove a cyst, Montoya said she wanted support in the hospital but did not have any options available to her.

From Los Angeles Times Mar. 18, 2026

Agnew and Hamilton knew from their years practicing military surgery that the human body often encases a bullet in a cyst, or sac, making it harmless.

From "Ambushed!" by Gail Jarrow

Over time, these cysts can impair kidney function and eventually lead to kidney failure.

From Science Daily Jun. 17, 2026

"This is not just cysts in women's ovaries," she said.

From BBC May 31, 2026

The change reflects a broader scientific understanding of the condition as a multisystem disorder that affects metabolic, hormonal, reproductive and mental health — not simply a condition defined by ovarian cysts.

From Salon May 16, 2026

During her GCSEs she made repeated hospital visits but was told cysts and growths found during ultrasounds would pass on their own.

From BBC Mar. 16, 2026

Some had crooked backs, or humps, or horns, or antlers, or bulging cysts, or tails.

From "Fablehaven" by Brandon Mull

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