doxorubicin

American  

[dok-suh-roo-buh-sin] / ˌdɒk səˈru bə sɪn /

noun

Pharmacology.

1. a cytotoxic antibiotic, C 27 H 29 NO 11 , derived from a variety of the bacterium Streptomyces peucetius and used in the treatment of sarcoma, malignant lymphoma, acute leukemia, and other cancers: administered intravenously, it is noted for its bright red color and potentially dangerous side effects.

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Etymology

Origin of doxorubicin

First recorded in 1970–75; d(e)ox(y)- + -o- + Latin rub(er) “red” (alluding to its color; rubric, red ¹ ) + -i- + -(my)cin

Example Sentences

Though more research is needed, the researchers said their findings suggest that combining doxorubicin and THZ1 could help prevent heart damage and increase the effectiveness of chemotherapy treatment.

From Science Daily • Jun. 3, 2024

The mouse was destined for a study looking at whether vigorous exercise can limit heart problems caused by doxorubicin, which is also known as Adriamycin and is an anthracycline.

From Washington Post • Dec. 25, 2016

But in 1996, after Mary's experience with the highly toxic chemotherapy drug doxorubicin — dubbed the ‘red death’ — he heeded her plea and went to work.

From Scientific American • Jul. 1, 2014

But in 1996, after Mary's experience with the highly toxic chemotherapy drug doxorubicin — dubbed the 'red death' — he heeded her plea and went to work.

From Nature • May 27, 2014

The two drugs are doxorubicin and methotrexate, and in both cases supplies in the United States are being bolstered by shipments from abroad.

From New York Times • Feb. 21, 2012