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Synonyms

degenerative

American  
[dih-jen-er-uh-tiv, -uh-rey-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /

adjective

  1. tending to degenerate.

  2. characterized by degeneration.


degenerative British  
/ dɪˈdʒɛnəˌreɪtɪv /

adjective

  1. (of a disease or condition) getting steadily worse

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of degenerative

First recorded in 1840–50; degenerate + -ive

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

While cerebral palsy is not degenerative, as Vicky ages she experiences increased stiffness, fatigue and secondary health challenges.

From BBC • May 14, 2026

The mustached southerner, yachting enthusiast and philanthropist, whose empire also included sports clubs, had been suffering from the degenerative disease Lewy Body Dementia.

From Barron's • May 6, 2026

A handful were posthumously diagnosed with chronic traumatic encephalopathy, the progressive, degenerative brain disease found in people with a history of repetitive head impacts.

From Los Angeles Times • Mar. 23, 2026

Petrou was diagnosed with retinitis pigmentosa, a degenerative disorder that leads to vision loss, at age 18.

From The Wall Street Journal • Mar. 12, 2026

Because these small amounts of pesticides are cumulatively stored and only slowly excreted, the threat of chronic poisoning and degenerative changes of the liver and other organs is very real.

From "Silent Spring" by Rachel Carson

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