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Synonyms

degenerative

American  
[dih-jen-er-uh-tiv, -uh-rey-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /

adjective

  1. tending to degenerate.

  2. characterized by degeneration.


degenerative British  
/ dɪˈdʒɛnəˌreɪtɪv /

adjective

  1. (of a disease or condition) getting steadily worse

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of degenerative

First recorded in 1840–50; degenerate + -ive

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

I had vaguely heard about MS but I really knew nothing about the degenerative disease.

From BBC Aug. 28, 2026

For now, regular cardiology care remains the practical priority for people with degenerative mitral regurgitation.

From Science Daily Jul. 12, 2026

CTE is a degenerative brain disease that has been found in people who experience repetitive head trauma and can be diagnosed only after death.

From Los Angeles Times Jul. 7, 2026

In setting out Jonathan’s defense, one of the filing’s most striking assertions is that Isak suffered from bilateral gonarthrosis in both knees, a degenerative joint condition that causes cartilage wear, pain, stiffness and reduced mobility.

From The Wall Street Journal May 28, 2026

The distinguished historian Tony Judt, who died in mid-2010 of motor neuron disease, used it to compose essays after his degenerative disease robbed him of the ability to move.

From "Words Like Loaded Pistols" by Sam Leith

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