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Synonyms

degenerative

American  
[dih-jen-er-uh-tiv, -uh-ray-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /

adjective

  1. tending to degenerate.

  2. characterized by degeneration.


degenerative British  
/ dɪˈdʒɛnəˌreɪtɪv /

adjective

  1. (of a disease or condition) getting steadily worse

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms


Etymology

Origin of degenerative

First recorded in 1840–50; degenerate + -ive


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

CTE, which stands for chronic traumatic encephalopathy, is a degenerative brain disease involving the buildup in the brain of “tau” proteins associated with forms of dementia such as Alzheimer’s.

From MarketWatch ● Sep. 30, 2026

At least a quarter of National Football League players may end up with a degenerative brain disease, according to a new study published Tuesday that lays bare the extreme toll of America's favorite sport.

From Barron's ● Aug. 25, 2026

CTE is a degenerative brain disease that has been found in people who experience repetitive head trauma and can be diagnosed only after death.

From Los Angeles Times ● Jul. 7, 2026

Osteoarthritis is a degenerative joint disease that affects millions of people each year and can occur in many different joints throughout the body.

From Science Daily ● Jun. 23, 2026

The distinguished historian Tony Judt, who died in mid-2010 of motor neuron disease, used it to compose essays after his degenerative disease robbed him of the ability to move.

From "Words Like Loaded Pistols" by Sam Leith

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