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Synonyms

degenerative

American  
[dih-jen-er-uh-tiv, -uh-ray-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /

adjective

  1. tending to degenerate.

  2. characterized by degeneration.


degenerative British  
/ dɪˈdʒɛnəˌreɪtɪv /

adjective

  1. (of a disease or condition) getting steadily worse

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms


Etymology

Origin of degenerative

First recorded in 1840–50; degenerate + -ive


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Osteoarthritis is a degenerative joint disease in which cartilage gradually breaks down, leaving joints painful, swollen and increasingly difficult to move.

From Science Daily ● Oct. 6, 2026

CTE, which stands for chronic traumatic encephalopathy, is a degenerative brain disease involving the buildup in the brain of “tau” proteins associated with forms of dementia such as Alzheimer’s.

From MarketWatch ● Sep. 30, 2026

Parkinson's disease is a chronic, degenerative neurological disorder that affects the body's motor system, often causing shaking and other difficulties in movement.

From Barron's ● Jul. 27, 2026

CTE is a degenerative brain disease that has been found in people who experience repetitive head trauma and can be diagnosed only after death.

From Los Angeles Times ● Jul. 7, 2026

Katie leaned forward, and I whispered the many problems I’d been suffering, which had led to the diagnosis of chronic, degenerative, relapsing-remitting inflammobetigoitis.

From "Liar, Liar" by Gary Paulsen

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