degranulation
Americannoun
Etymology
Origin of degranulation
First recorded in 1940–45; de- + granulation
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
They eliminate these threats through a process called degranulation, which releases a protein known as perforin.
From Science Daily ● Oct. 11, 2025
This led to changes in the expression levels of the IgE-receptor, which ultimately inhibited degranulation in MCs.
From Science Daily ● Feb. 1, 2024
These substances interact with EP3 receptors in MCs and prevent degranulation, limiting the release of histamine and minimizing allergic response.
From Science Daily ● Feb. 1, 2024
Allergies and allergic asthma are mediated by mast cell degranulation that is caused by the crosslinking of the antigen-specific IgE molecules on the mast cell surface.
From Textbooks ● Jun. 19, 2013
As these mediators are released with mast cell degranulation, type I hypersensitivity reactions are usually rapid and occur within just a few minutes, hence the term immediate hypersensitivity.
From Textbooks ● Jun. 19, 2013
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
