demyelinate

American  

[dih-mahy-uh-luh-neyt] / dɪˈmaɪ ə ləˌneɪt /

verb (used with object)

demyelinated, demyelinating

1. to obliterate or remove the myelin sheath from (a nerve or nerves).

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Etymology

Origin of demyelinate

First recorded in 1960–65; de- + myelin + -ate ¹

Example Sentences

See Examples For:

demyelinating

The continuation of other studies with riliprubart, including another phase 3 trial for chronic inflammatory demyelinating polyneuropathy, will be evaluated in light of the data, Sanofi said.

From The Wall Street Journal ● Jun. 10, 2026

The research paper is titled "Decreased mitochondrial activity in the demyelinating cerebellum of progressive multiple sclerosis and chronic EAE contributes to Purkinje cell loss."

From Science Daily ● Jan. 6, 2026

In demyelinating diseases like multiple sclerosis, action potential conduction slows because current leaks from previously insulated axon areas.

From Textbooks ● Jun. 9, 2022

Unlike Epstein-Barr, MS, a devastating demyelinating disease of the central nervous system, is relatively rare.

From Scientific American ● Jan. 13, 2022

Its intravenous form is FDA-licensed for six conditions, including primary immunodeficiencies; Kawasaki disease, which causes inflammation in the blood vessels; preventive care after bone marrow transplants; and a neurological condition called chronic inflammatory demyelinating polyneuropathy.

From Washington Post ● Sep. 20, 2019