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demyelinate

American  
[dih-mahy-uh-luh-nayt] / dɪˈmaɪ ə ləˌneɪt /

verb (used with object)

demyelinated, demyelinating
  1. to obliterate or remove the myelin sheath from (a nerve or nerves).


Etymology

Origin of demyelinate

First recorded in 1960–65; de- + myelin + -ate 1


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

The continuation of other studies with riliprubart, including another phase 3 trial for chronic inflammatory demyelinating polyneuropathy, will be evaluated in light of the data, Sanofi said.

From The Wall Street Journal ● Jun. 10, 2026

Li noted that previous studies have suggested a role for OPCs in a range of neurodegenerative conditions, including demyelinating disorders such as MS, neurodegenerative diseases such as Alzheimer's and even psychiatric disorders like schizophrenia.

From Science Daily ● Jan. 14, 2024

In demyelinating diseases like multiple sclerosis, action potential conduction slows because current leaks from previously insulated axon areas.

From Textbooks ● Jun. 9, 2022

Unlike Epstein-Barr, MS, a devastating demyelinating disease of the central nervous system, is relatively rare.

From Scientific American ● Jan. 13, 2022

Its intravenous form is FDA-licensed for six conditions, including primary immunodeficiencies; Kawasaki disease, which causes inflammation in the blood vessels; preventive care after bone marrow transplants; and a neurological condition called chronic inflammatory demyelinating polyneuropathy.

From Washington Post ● Sep. 20, 2019

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