major depressive disorder

American  

[may-jer-di-pres-iv-dis-awr-der] / ˈmeɪ dʒər dɪˈprɛs ɪv dɪsˈɔr dər /

noun

1. Psychiatry. an affective disorder characterized by a sustained period of low mood, diminished self-esteem, and reduced interest in normally enjoyable activities.

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Example Sentences

Of these participants, 259 had schizophrenia and 177 had affective disorders that included bipolar disorder and major depressive disorder with psychosis.

From Science Daily

Patients living with major depressive disorder, including those who have not improved with commonly prescribed antidepressants, may benefit from short-term nitrous oxide treatment, according to a large meta-analysis led by the University of Birmingham.

From Science Daily

Antidepressants are typically prescribed for people with major depressive disorder.

From The Wall Street Journal

"This is the first time we've been able to identify what specific brain cell types are affected in depression by mapping gene activity together with mechanisms that regulate the DNA code," said senior author Dr. Gustavo Turecki, a professor at McGill, clinician-scientist at the Douglas Institute and Canada Research Chair in Major Depressive Disorder and Suicide.

From Science Daily

A group of 82 participants with major depressive disorder was assessed using two innovative methods.

From Science Daily