loss of hope; hopelessness.
someone or something that causes hopelessness: He is the despair of his mother.
to lose, give up, or be without hope (often followed by of): to despair of humanity.
Obsolete. to give up hope of.
- de·spair·er, noun
- self-de·spair, noun
- un·de·spaired, adjective
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
How to use despair in a sentence
This disease loves isolation, and we know all about loneliness and despair, and we can’t stay well in recovery if we’re not connecting with people.What was lost when covid forced addiction support groups online — and what was gained | Allyson Chiu | November 23, 2020 | Washington Post
In Studio Theatre’s audio-drama production, actor Gina Daniels infuses the slogan with a delectable mixture of snark, exasperation and weariness, seasoned with a grain of despair.Audio adaptation of Beltway drama ‘Kings’ tantalizes but ultimately falls flat without a stage | Celia Wren | November 5, 2020 | Washington Post
Psychiatric disorders plausibly related to a sense of despair, such as major depression and anxiety disorders, have been studied for decades.‘Deaths of despair’ are rising. It’s time to define despair | Bruce Bower | November 2, 2020 | Science News
Developing a despair scale may also provide insights into those individuals most likely to succumb to despair-related fatalities.‘Deaths of despair’ are rising. It’s time to define despair | Bruce Bower | November 2, 2020 | Science News
Many despair that their labor will ever decently shelter their families or protect them against disease.Nobel Peace Prize Spotlights The Links Between Hunger And Conflict | LGBTQ-Editor | October 10, 2020 | No Straight News
The only common ground to be found in this despaired summer is that unlike my kids, those in Gaza simply were in the wrong place.
Many of his supporters had despaired that the regime would ever let him out.
All these years later, the carnage continues and many of us have despaired at ever ending it.
Aronson claims "Fayyad has evidently despaired of his failed state-building strategy."
Take the gay and lesbian community: for two years they despaired, imagining Obama had forgotten the support they had given him.Obama’s Second-Term Surprise: Politics Not As Usual | James Warren | November 8, 2012 | THE DAILY BEAST
They obeyed, and the third day after brought to us the sufferer, whose life they had despaired of, in a half-dying condition.
But Samuel Adams, who thought "nothing should be despaired of," took upon himself the performance of this arduous task.The Eve of the Revolution | Carl Becker
He would candidly avow, however, that he despaired of seeing the question brought to a speedy and satisfactory settlement.The History of England in Three Volumes, Vol.III. | E. Farr and E. H. Nolan
We were compelled to abandon the undertaking; and despaired of ever being able to succeed in building any thing of the kind.
From that night, however, I never absolutely despaired, even when things looked their very worst.The Adventures of Louis de Rougemont | Louis de Rougemont
British Dictionary definitions for despair
(intr often foll by of) to lose or give up hope: I despair of his coming
(tr) obsolete to give up hope of; lose hope in
total loss of hope
a person or thing that causes hopelessness or for which there is no hope
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012