DNA repair

Cultural  

1. The way in which a cell corrects potentially damaging or mutagenic errors in its DNA. (See mutagen.) DNA bases may be directly replaced by enzymes, or part of a strand may be replaced by enzymes using its opposite, paired strand as a template.

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Example Sentences

Once activated, Cul4A works together with an adaptor protein called WDR5 to target DNA repair proteins such as RAD51 for destruction.

From Science Daily • Jun. 10, 2026

This system marks specific proteins for destruction, effectively dismantling key components of the DNA repair network.

From Science Daily • Jun. 10, 2026

DNA repair proteins inside cells are constantly being produced and removed to maintain a healthy balance.

From Science Daily • Jun. 10, 2026

Co-corresponding author Professor Joo-Yong Lee stated, "We identified a mechanism in which key DNA repair proteins are actively degraded inside the cell. This provides a new way to regulate homologous recombination beyond genetic mutations."

From Science Daily • Jun. 10, 2026

Co-corresponding author Director Kyungjae Myung remarked, "This study demonstrates that controlling the stability of DNA repair proteins can directly impact cancer cell survival. It also highlights a new therapeutic direction for overcoming drug resistance."

From Science Daily • Jun. 10, 2026