DNA sequencing

British  

noun

1. the procedure of determining the order of base pairs in a section of DNA

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DNA sequencing Scientific  

1. The determination of the sequence of nucleotides in a sample of DNA.

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DNA sequencing Cultural  

1. A process by which the sequence of nucleotides along a strand of DNA is determined. Originally a difficult process to carry out, DNA sequencing can now be done routinely by machines. The completion of the Human Genome Project in 2000 produced the largest DNA sequence ever assembled. To carry out the sequencing of the human genome, scientists cut the DNA up into short fragments, sequenced these fragments simultaneously, and then assembled the entire genome by using sophisticated computer techniques to match the fragments to each other.

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Many believe that knowledge of the human genome will lead to enormous advances in medicine. (Compare gene mapping and DNA fingerprinting.)

Example Sentences

Using cutting-edge DNA sequencing and an advanced stem cell research model, an international group of scientists has identified a previously unknown form of diabetes that affects babies.

From Science Daily • Jan. 14, 2026

Originally excavated in 1981 from the grounds of St Giles' Cathedral, the remains have undergone new detailed analysis using advanced methods including ancient DNA sequencing, isotopic analysis and radiocarbon dating.

From BBC • Nov. 3, 2025

Using advanced DNA sequencing tools, researchers compared two closely related species: Dysdera catalonica, which inhabits parts of Catalonia and southern France, and D. tilosensis, native to the island of Gran Canaria.

From Science Daily • Nov. 2, 2025

Using DNA sequencing technologies, we were able to identify and quantify the microbes detected in each sample.

From Salon • Jan. 13, 2025

Now, after a heroic DNA sequencing effort, a collaboration involving hundreds of scientists has created a new family tree for flowering plants.

From New York Times • May 11, 2024