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Down's syndrome

British  

noun

    1. Former name: mongolism. Technical name: trisomy 21. offensive pathol a condition caused by the presence of an extra copy of chromosome 21 resulting in learning difficulties and physical differences, such as shorter stature

    2. ( as modifier )

      a Down's syndrome baby

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Down's syndrome Cultural  
  1. A congenital condition, caused by an abnormality in the chromosomes, marked by moderate to severe mental retardation and changes in certain physical features.


Usage

Although the condition was once generally known as mongolism , this term has been considered offensive since the early 1960s. The terms Down's syndrome or ( US ) Down syndrom are now preferred.

Etymology

Origin of Down's syndrome

C19: after John Langdon-Down (1828–96), English physician

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Ailith Harley-Roberts, whose daughter Thalia has Down's syndrome, says the government plans have prompted concern among parents she knows through her charity Sunshine and Smiles, which supports families like hers.

From BBC ● Feb. 24, 2026

Carers, parents and other young people with conditions like cerebral palsy and Down's syndrome are also welcome.

From BBC ● Feb. 6, 2026

His father Brian said it was an "extremely worrying and traumatic" time and he believed if Joel, who has Down's syndrome, had been vaccinated he would not have needed hospital treatment.

From BBC ● Jan. 13, 2026

Dot Gallagher's son Michael, 38, is in a relationship with Alison Williams, 42, and they both have Down's syndrome.

From BBC ● Dec. 28, 2025

The presenter, who has Down's syndrome, says: "I'm looking forward to sword fighting, the Tinkerbell stuff - everything really, it's just so exciting."

From BBC ● Sep. 9, 2025

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