efavirenz

[uh-fah-vi-renz]

noun

Pharmacology.

1. a nonnucleoside reverse transcriptase inhibitor used with other medications to treat HIV infection in patients who have or do not have AIDS.

Word History and Origins

Origin of efavirenz¹

First recorded in 1950–55; shortening of e(thyne) ( def. ) + f(luoro-) ( def. ) + vir(us) ( def. ) + (b)enz(yl) ( def. )

Example Sentences

This line of inquiry follows animal model and stem cell studies in which efavirenz reduced the accumulation of both amyloid beta and tau.

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Efavirenz may reduce brain cholesterol.

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Separately, researchers are conducting a study at the Amsterdam University Medical Center involving a different HIV medicine, efavirenz.

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After determining that older mice had more CYP46A1 in their inner ears than younger mice, and therefore had less cholesterol, the researchers used an HIV drug called efavirenz to induce hearing loss in mice.

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The third group used the standard of care in South Africa, which is tenofovir, FTC, and efavirenz.

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