endostatin

American  

[en-doh-stat-n] / ˌɛn doʊˈstæt n /

noun

Biochemistry.

1. a naturally occurring protein, collagen 18, that interferes with the growth of new blood vessels: investigated for use as an anticancer drug.

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Etymology

Origin of endostatin

First recorded in 1995–2000; endo(thelial) ( def. ) + -stat ( def. ) + -in ² ( def. )

Example Sentences

So what if angiostatin and endostatin work only in mice?

From Time Magazine Archive

No one knows yet whether angiostatin and endostatin will help people.

From Time Magazine Archive

When scientists first started making endostatin, it took 200 qt. of mouse urine to obtain less than a millionth of an ounce.

From Time Magazine Archive

Not, that is, until Folkman and O'Reilly added to the mix a second molecular fragment, which they called endostatin, from yet another naturally occurring protein.

From Time Magazine Archive

Meanwhile, they injected one group of mice with endostatin, another with a different blood-vessel inhibitor called TNP-470 and a control group with an inert saline solution.

From Time Magazine Archive