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endostatin

American  
[en-doh-stat-n] / ˌɛn doʊˈstæt n /

noun

Biochemistry.
  1. a naturally occurring protein, collagen 18, that interferes with the growth of new blood vessels: investigated for use as an anticancer drug.


Etymology

Origin of endostatin

First recorded in 1995–2000; endo(thelial) ( def. ) + -stat ( def. ) + -in 2 ( def. )

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

At this stage all EntreMed can offer is some very interesting molecules, called angiostatin and endostatin, and the only cancers they have cured so far have been in mice.

From Time Magazine Archive

How fast those studies can begin depends on how much angiostatin and endostatin EntreMed and its business partner, Bristol-Myers Squibb, can produce and whether they can figure out which fragment to focus on first.

From Time Magazine Archive

EntreMed claims it now has a way to make lots of endostatin, using yeast cells as tiny factories; angiostatin is proving a lot tougher to mass-produce.

From Time Magazine Archive

Reassured, the N.C.I. gave the go-ahead for clinical trials of endostatin later this year on patients with advanced tumors.

From Time Magazine Archive

When scientists first started making endostatin, it took 200 qt. of mouse urine to obtain less than a millionth of an ounce.

From Time Magazine Archive

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