fibrinogen

American  

[fahy-brin-uh-juhn] / faɪˈbrɪn ə dʒən /

noun

Biochemistry.

1. a globulin occurring in blood and yielding fibrin in blood coagulation.

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fibrinogen British  

/ ˌfaɪbrɪnəʊˈdʒɛnɪk, ˌfaɪbrɪˈnɒdʒənəs, fɪˈbrɪnədʒən /

noun

1. a soluble protein, a globulin, in blood plasma, converted to fibrin by the action of the enzyme thrombin when blood clots

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fibrinogen Scientific  

/ fī-brĭn′ə-jən /

1. A protein in the blood plasma that is essential for the coagulation of blood. It is converted to fibrin by the action of thrombin in the presence of calcium ions.

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Other Word Forms

• fibrinogenic adjective

Etymology

Origin of fibrinogen

First recorded in 1870–75; fibrino- + -gen

Compare meaning

How does fibrinogen compare to similar and commonly confused words? Explore the most common comparisons:

• fibrin vs. fibrinogen

Example Sentences

"But when the two complex together, you only need very small amounts of each to cause damage. There's a synergistic effect with Aβ and fibrinogen."

From Science Daily • Oct. 22, 2025

"It takes a larger amount of Aβ or fibrinogen alone to cause serious damage in the Alzheimer's brain," says Erin Norris, research associate professor in the laboratory of Sidney Strickland at Rockefeller.

From Science Daily • Oct. 22, 2025

Their experiments revealed that while Aβ and fibrinogen alone caused little harm, even small amounts of the combined complex led to major problems.

From Science Daily • Oct. 22, 2025

But elevated fibrinogen seemed to correlate with brain fog whether or not a person previously had COVID, which indicated that cognitive problems caused by other conditions may also involve fibrinogen.

From Scientific American • Sep. 1, 2023

The constituent substance which is present in the first-named fluids is known as fibrinogen, and that present in the serum or the clot is known as fibrin-ferment or thrombin.

From Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" by Various