fibrinogen

American  

[fahy-brin-uh-juhn] / faɪˈbrɪn ə dʒən /

noun

Biochemistry.

1. a globulin occurring in blood and yielding fibrin in blood coagulation.

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fibrinogen British  

/ ˌfaɪbrɪnəʊˈdʒɛnɪk, ˌfaɪbrɪˈnɒdʒənəs, fɪˈbrɪnədʒən /

noun

1. a soluble protein, a globulin, in blood plasma, converted to fibrin by the action of the enzyme thrombin when blood clots

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fibrinogen Scientific  

/ fī-brĭn′ə-jən /

1. A protein in the blood plasma that is essential for the coagulation of blood. It is converted to fibrin by the action of thrombin in the presence of calcium ions.

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Other Word Forms

• fibrinogenic
  adjective

Etymology

Origin of fibrinogen

First recorded in 1870–75; fibrino- + -gen

Compare meaning

How does fibrinogen compare to similar and commonly confused words? Explore the most common comparisons:

• fibrin vs. fibrinogen

Example Sentences

See Examples For:

fibrinogen

A humanized antibody that blocks the inflammatory region of fibrinogen is currently in phase-1 trials after animal studies showed protection against neuronal loss.

From Science Daily ● Jan. 8, 2026

When Aβ attaches to fibrinogen, it produces unusual clots that resist breakdown.

From Science Daily ● Oct. 22, 2025

She, along with summer intern Amelia Staats, found that fibrinogen, a protein involved in blood clotting, is a key culprit in signal interference.

From Science Daily ● Oct. 3, 2023

These clots often contain misfolded fibrinogen proteins that prevent the clots from breaking down, and this effect can clog blood vessels and block oxygen flow to the brain and other organs.

From Scientific American ● Sep. 1, 2023

This is known as fibrinoglobulin, and apparently it arises from the fibrinogen, so that the change would be one of cleavage into fibrin and fibrinoglobulin.

From Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" by Various