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fibronectin

American

[fahy-bruh-nek-tin] / ˌfaɪ brəˈnɛk tɪn /

noun

Cell Biology.

a fibrous protein that binds to collagen, fibrin, and other proteins and also to the cell membranes, functioning as an anchor and connector.

fibronectin Scientific

/ fī′brə-nĕk′tn /

Any of several glycoproteins that occur especially in plasma and in soft connective tissue. Fibronectins are important for the adhesion of fibrous extracellular tissue matrices and also play roles in cellular adhesion, embryonic cellular differentiation, phagocytosis, and the aggregation of platelets in blood clotting.

Etymology

Origin of fibronectin

1975–80; fibro- + Latin nect ( ere ) to bind, join together ( see connect, nexus) + -in ²

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

fibronectin

Increasing fibronectin in these cells was enough to disrupt the barrier, allowing it to become more permeable.

From Science Daily ● Oct. 19, 2026

Analyses of brain tissue and cerebrospinal fluid showed that elevated fibronectin levels were associated with inflammation in astrocytes.

From Science Daily ● Oct. 19, 2026

The researchers increased human fibronectin specifically in astrocytes, specialized support cells that help maintain the blood-brain barrier and keep the brain functioning properly.

From Science Daily ● Oct. 19, 2026

Another would involve blocking the abnormal cellular signals triggered by excess fibronectin.

From Science Daily ● Oct. 19, 2026

Several of the aptamers attached to a variation of fibronectin, a protein found on the surface of mouse cells.

From Science Daily ● May 15, 2026

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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023