first-line
Americanadjective
-
available for immediate service, especially combat service.
first-line troops.
-
of prime importance or quality.
adjective
Etymology
Origin of first-line
First recorded in 1895–1900
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Investors are bullish on AstraZeneca’s trial for camizestrant as a first-line treatment for breast cancer, the analysts say.
From The Wall Street Journal • May 21, 2026
Each time, the first-line representative said no, suggesting something like, “If you can’t afford to pay it now, set up a payment plan or apply for financial assistance.”
From Slate • Apr. 25, 2026
Nektar stock jumped 26% after positive trial results, with analysts raising price targets and expecting first-line treatment potential.
From Barron's • Apr. 20, 2026
For over 60 years, metformin has been a first-line treatment for type 2 diabetes, yet scientists have not fully understood how it works.
From Science Daily • Mar. 25, 2026
He was put on a standard regimen of four first-line antibiotics, similar to what WHO recommended for anyone who contracted TB.
From "Mountains Beyond Mountains" by Tracy Kidder and Michael French
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Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.