gene amplification

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noun Genetics.

an increase in the frequency of replication of a DNA segment.

such an increase induced by a polymerase chain reaction.

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Also called genetic amplification, DNA amplification .

Origin of gene amplification

First recorded in 1970–75

Words nearby gene amplification

gender-specific, gene, geneal., genealogical tree, genealogy, gene amplification, genearch, gene bank, gene clone, genecology, gene doping

Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2022

How to use gene amplification in a sentence

It got it all out there… Gene Hackman and Douglas… Melvyn Douglas is amazing.
The Story Behind Lee Marvin’s Liberty Valance Smile|Robert Ward|January 3, 2015|DAILY BEAST
Was the blackface scene with Gene Wilder in Silver Streak an important step in how American audiences view minstrelsy?
How Richard Pryor Beat Bill Cosby and Transformed America|David Yaffe, Scott Saul|December 10, 2014|DAILY BEAST
Another week, another study declaring the hunt for the ‘gay gene’ over.
The Problematic Hunt for a ‘Gay Gene’|Samantha Allen|November 20, 2014|DAILY BEAST
Rev. V. Gene Robinson is a Senior Fellow at the Center for American Progress, Washington, DC.
When Police Violence Gets Personal|Gene Robinson|October 5, 2014|DAILY BEAST

You see, as far as passing the baton down, Michael used to look at Fred Astaire, Gene Kelly, and James Brown.
Quincy Jones Talks Chicago’s Mean Streets, Why Kanye West Is No Michael Jackson, and Bieber|Marlow Stern|September 25, 2014|DAILY BEAST
Amplification, declamation, and exaggeration were at all times the faults of the Greeks, excepting Demosthenes and Aristotle.
A Philosophical Dictionary, Volume 1 (of 10)|Franois-Marie Arouet (AKA Voltaire)
Nearly all that she says would be tiresome amplification if any other was speaking of Phædra's passion.
A Philosophical Dictionary, Volume 1 (of 10)|Franois-Marie Arouet (AKA Voltaire)
However, there are times when this cannot be done: a point may be so well known that it needs no amplification.
English: Composition and Literature|W. F. (William Franklin) Webster
He could hear his voice boom out with thunderous amplification and saw Scotty clap his hands to his ears.
The Flaming Mountain|Harold Leland Goodwin
"Because of the limit of amplification in the tubes," Arcot replied.
Islands of Space|John W Campbell

Scientific definitions for gene amplification

gene amplification

An increase in the number of copies of a gene in a cell, resulting in an elevation in the level of the RNA or protein encoded for by the gene and a corresponding amplification of the phenotype that the gene confers on the cell. Drug resistance in cancer cells is linked to amplification of the gene that prevents absorption of the chemotherapeutic agent by the cell.

Cultural definitions for gene amplification

gene amplification

A process in a cell by which a particular gene is replicated so that more copies are available to produce a protein for the cell's use. For example, the genes that code for proteins involved in ribosomes are amplified early in the process of cell development so that there are sufficient numbers of them to assemble the cell.

notes for gene amplification

PCR, polymerase chain reaction, can be considered a type of man-made gene amplification process.