Mesopotamia

American  

[mes-uh-puh-tey-mee-uh] / ˌmɛs ə pəˈteɪ mi ə /

noun

1. an ancient region in W Asia between the Tigris and Euphrates rivers: now part of Iraq.

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Mesopotamia British  

/ ˌmɛsəpəˈteɪmɪə /

noun

1. a region of SW Asia between the lower and middle reaches of the Tigris and Euphrates rivers: site of several ancient civilizations

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Mesopotamia Cultural  

1. A region of western Asia, in what is now Iraq, known as the “cradle of civilization.” Western writing first developed there, done with sticks on clay tablets. Agricultural organization on a large scale also began in Mesopotamia, along with work in bronze and iron (see Bronze Age and Iron Age). Governmental systems in the region were especially advanced (see Babylon (see also Babylon) and Hammurabi). A number of peoples lived in Mesopotamia, including the Sumerians, Akkadians, Hittites, and Assyrians.

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Other Word Forms

• Mesopotamian
  adjective

Etymology

Origin of Mesopotamia

Latin from Greek mesopotamia ( khora ) (the land) between rivers

Example Sentences

See Examples For:

Mesopotamia

Granulation dates to Mesopotamia, but the Etruscans elevated the practice, using granules as small as 0.14 millimeter in diameter, one-seventh the size of those used by Mesopotamians and Egyptians.

From The Wall Street Journal ● Jul. 18, 2026

Traveling extensively with her archaeologist husband in Mesopotamia, Christie was adamant that “all I needed was a steady table and a typewriter.”

From The Wall Street Journal ● Mar. 27, 2026

Traditionally historians date the first written words to proto-cuneiform scripts made around 5,000 years ago in ancient Iraq, or Mesopotamia.

From BBC ● Feb. 26, 2026

Founded around 2000 BCE in Mesopotamia, Babylon grew into the largest city of its time and became a thriving center of culture and scholarship.

From Science Daily ● Nov. 11, 2025

Mesopotamia had a legacy of astronomical observation going back at least a thousand years before the classical era.

From "Circumference" by Nicholas Nicastro