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glucagon

American  
[gloo-kuh-gon] / ˈglu kəˌgɒn /

noun

Biochemistry.
  1. a hormone secreted by the pancreas that acts in opposition to insulin in the regulation of blood glucose levels.


glucagon British  
/ ˈɡluːkəˌɡɒn, -ɡən /

noun

  1. a polypeptide hormone, produced in the pancreas by the islets of Langerhans, that stimulates the release of glucose into the blood Compare insulin

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

glucagon Scientific  
/ glo̅o̅′kə-gŏn′ /
  1. A polypeptide hormone produced by the pancreas that stimulates an increase in blood glucose levels, thus opposing the action of insulin.


Etymology

Origin of glucagon

1923; probably gluc- + Greek ágōn present participle of ágein to lead, drive; see -agogue


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

At the same time, consuming fat before glucose stimulated an early increase in several hormones, including glucagon, GIP, and GLP-1.

From Science Daily ● Oct. 11, 2026

The drug, a once-weekly shot that combines GLP-1, GIP and glucagon, is the most effective yet, helping people lose up to 28% of their body weight in clinical trials.

From MarketWatch ● Aug. 12, 2026

Retatrutide is a so-called triple hormone receptor agonist, which works by activating the body’s receptors for glucagon-like peptide-1, or GLP-1, glucose-dependent insulinotropic polypeptide and glucagon, hormones that regulate blood sugar and digestion.

From The Wall Street Journal ● May 21, 2026

UBT251 is what’s known as a triple G weight-loss agonist—meaning it combines the hormones GLP-1, GIP, and glucagon.

From Barron's ● Feb. 24, 2026

Laila Soueif was hospitalised last Thursday and given glucagon, a hormone used to treat severe hypoglycaemia.

From BBC ● Jun. 3, 2025

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