glucocorticoid

American  

[gloo-koh-kawr-ti-koid] / ˌglu koʊˈkɔr tɪˌkɔɪd /

noun

Biochemistry.

1. any of a class of steroid hormones that are synthesized by the adrenal cortex of vertebrates and have anti-inflammatory activity.

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glucocorticoid British  

/ ˌɡluːkəʊˈkɔːtɪˌkɔɪd /

noun

1. any of a class of corticosteroids that control carbohydrate, protein, and fat metabolism and have anti-inflammatory activity

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Etymology

Origin of glucocorticoid

1945–50; gluco- + cortic(o)- ( def. ) + -oid; cf. corticosteroid

Example Sentences

See Examples For:

glucocorticoid

Coregulator proteins were identified as an alternative target through which the glucocorticoid receptor affects the regulation of gene expression.

From Science Daily ● Apr. 10, 2024

However, recent studies have shown that the glucocorticoid receptor also has an oncogenic, or cancer-promoting, effect in cancers like breast and prostate cancer.

From Science Daily ● Apr. 10, 2024

"This study showed that the glucocorticoid receptor can only use regulatory regions that are already active in prostate cancer cells," says Doctoral Researcher Laura Helminen of the University of Eastern Finland.

From Science Daily ● Apr. 10, 2024

This is because FOXA1 was found to be involved in the silencing of the glucocorticoid receptor gene, and this is what increased its activity when FOXA1 was inhibited.

From Science Daily ● Apr. 10, 2024

The researchers studied how these immune cells -- derived in this case from mice -- responded to inflammatory stimuli in a laboratory setting and what effects additional administration of a glucocorticoid had.

From Science Daily ● Apr. 10, 2024