glucocorticoid

American  

[gloo-koh-kawr-ti-koid] / ˌglu koʊˈkɔr tɪˌkɔɪd /

noun

Biochemistry.

1. any of a class of steroid hormones that are synthesized by the adrenal cortex of vertebrates and have anti-inflammatory activity.

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glucocorticoid British  

/ ˌɡluːkəʊˈkɔːtɪˌkɔɪd /

noun

1. any of a class of corticosteroids that control carbohydrate, protein, and fat metabolism and have anti-inflammatory activity

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Etymology

Origin of glucocorticoid

1945–50; gluco- + cortic(o)- ( def. ) + -oid; cf. corticosteroid

Example Sentences

This is because FOXA1 was found to be involved in the silencing of the glucocorticoid receptor gene, and this is what increased its activity when FOXA1 was inhibited.

From Science Daily • Apr. 10, 2024

Glucocorticoids regulate vital biological processes by affecting gene encoding through a DNA-binding transcription factor, namely the glucocorticoid receptor.

From Science Daily • Apr. 10, 2024

Ultimately, inhibiting the activity of both the androgen and the glucocorticoid receptor was found to be primarily due to the limitation of FOXA1 activity.

From Science Daily • Apr. 10, 2024

The researchers studied how these immune cells -- derived in this case from mice -- responded to inflammatory stimuli in a laboratory setting and what effects additional administration of a glucocorticoid had.

From Science Daily • Apr. 10, 2024

Higher MIF levels are associated with glucocorticoid resistance, which means that our bodies are more prone to mount a more robust inflammatory response, he explained.

From Science Daily • Mar. 6, 2024