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graft-versus-host disease

American  
[graft-vur-suhs-hohst, grahft-] / ˈgræftˌvɜr səsˈhoʊst, ˈgrɑft- /

noun

  1. a reaction in which the cells of transplanted tissue immunologically attack the cells of the host organism, occurring especially in bone-marrow transplants.


Etymology

Origin of graft-versus-host disease

First recorded in 1970–75

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

I also experienced the risky complication known as graft-versus-host disease, in which donor immune cells, even when they are a lifesaving match, attack the recipient’s body—sometimes fatally.

From The Wall Street Journal ● Apr. 19, 2026

For the study, Dr. Kenderian and his team developed CAR-MSCs to specifically target a protein linked to a condition called graft-versus-host disease, as well as inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease.

From Science Daily ● Apr. 1, 2024

Self-derived stem cells could avoid the risks of graft-versus-host disease, a common and potentially deadly reaction that occurs when a patient's immune system perceives the transplant as a threat to be attacked.

From Science Daily ● Dec. 19, 2023

But finding a matching cell donor can be difficult, and a transplant can lead to graft-versus-host disease, a potentially deadly condition in which donor cells attack a patient’s cells.

From Science Magazine ● Aug. 11, 2021

Brown and the London patient also suffered from graft-versus-host disease as the transplanted immune systems attacked other recipient tissues as foreign.

From Science Magazine ● Mar. 4, 2019

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