graft-versus-host disease

American  

[graft-vur-suhs-hohst, grahft-] / ˈgræftˌvɜr səsˈhoʊst, ˈgrɑft- /

noun

1. a reaction in which the cells of transplanted tissue immunologically attack the cells of the host organism, occurring especially in bone-marrow transplants.

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Etymology

Origin of graft-versus-host disease

First recorded in 1970–75

Example Sentences

"In turn, the donated blood stem cells and the immune system they produce learn to not attack the recipient's tissues, and graft-versus-host disease can be avoided."

From Science Daily

None of the animals developed graft-versus-host disease, a condition in which the immune system arising from the donated blood stem cells attacks healthy tissue in the recipient, and the destruction of islet cells by the animals' original immune system came to a stop.

From Science Daily

A fully matched stem cell donor is preferred for stem cell transplant patients as it reduces the risk of graft-versus-host disease.

From Science Daily

Half-match stem cell transplants have become more common over the past decade as treatments to reduce graft-versus-host disease have improved, making such transplants safer.

From Science Daily

Even so, historical data suggest 10 - 15% of patients would experience severe graft-versus-host disease with standard treatment, according to the investigators.

From Science Daily